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Filtered Search Results
Apexbio Technology LLC Oxipurinol 2465-59-0 1g
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Oxipurinol (CAS 2465-59-0) is a small molecule inhibitor of xanthine oxidoreductase (XO) an enzyme integral to purine metabolism As the principal active metabolite of allopurinol oxipurinol functions as a noncompetitive XO inhibitor contributing significantly to the pharmacological effects observed with allopurinol therapy In vitro studies indicate that both allopurinol and oxipurinol demonstrate XO inhibition and exhibit free radical scavenging properties with evidence of cardioprotective effects independent of XO activity In vivo oxipurinol administration has been shown to reduce vascular free radical production in hypercholesterolemic animal models Its pharmacokinetic profile is characterized by predominant renal clearance Oxipurinol is widely utilized in research exploring oxidative stress cardiovascular physiology and disorders of purine metabolism
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Apexbio Technology LLC Asenapine 85650-56-2 1g
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Asenapine (CAS 85650-56-2) is a small-molecule psychotropic agent characterized by high-affinity antagonism at multiple neurotransmitter receptors including several serotonin (5-HT) dopamine noradrenaline and histamine receptor subtypes (with reported pK sub i /sub values in the high nanomolar to sub-nanomolar range such as 8 60 8 40 10 15 9 75 and 10 46) This broad receptor antagonism profile underlies its capacity to modulate neurotransmission in various central nervous system pathways Asenapine is widely employed in biomedical research to investigate the pharmacological basis of antipsychotic activity and to study the functional roles of monoaminergic and histaminergic signaling in psychiatric and neuropharmacological models
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Apexbio Technology LLC Lisinopril 76547-98-3 1g
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Lisinopril (CAS 76547-98-3) is a small molecule inhibitor of angiotensin-converting enzyme (ACE) By blocking ACE activity lisinopril reduces the formation of angiotensin II which diminishes vasoconstriction and aldosterone-mediated sodium and water retention resulting in reduced peripheral vascular resistance This compound is frequently utilized in biomedical research to investigate the pathophysiological mechanisms of hypertension congestive heart failure and cardiovascular disorders as well as to develop and validate preclinical pharmacological models related to ACE inhibition
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Apexbio Technology LLC Coenzyme Q0 605-94-7 1g
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Coenzyme Q0 (CAS 605-94-7) is a quinone derivative originally derived from cinnamon extract It modulates multiple cellular pathways by inducing apoptosis and autophagy primarily through inhibition of the HER-2/AKT/mTOR signaling cascade Additionally Coenzyme Q0 regulates transcription factors such as NF B and AP-1 enhances Nrf2 stability and mitigates inflammation and oxidative stress Its anti-angiogenic properties are mediated via downregulation of the MMP-9/NF- B pathway and upregulation of HO-1 signaling Coenzyme Q0 is widely used in basic research and drug development targeting cancer inflammation and angiogenesis-related disorders
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Apexbio Technology LLC Rebamipide 90098-04-7 1g
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Rebamipide (CAS 90098-04-7) is a small molecule administered orally and recognized for its gastroprotective properties Its primary mechanism involves upregulation of cyclooxygenase-2 (COX-2) expression which leads to increased endogenous prostaglandin synthesis particularly prostaglandin E2 (PGE2) thereby enhancing gastric mucosal defense Studies also indicate that rebamipide can inhibit the proliferation of gastric cancer cells This compound is utilized in research investigating the mechanisms underlying gastric mucosal injury peptic ulcer disease gastritis and gastric cancer
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SCP Science SODIUM IC STANDARD NA 1000P
NC3718051 SODIUM IC STANDARD NA 1000P
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Inorganic Ventures 1000µg/mL MALONATE 125mL
Inorganic Ventures' 1000 ppm (µg/mL) Malonate for IC is a 125mL certified reference material set in a water matrix for stability. This malonate standard is Traceable to NIST and manufactured in accordance with our stringent Quality Assurance guidelines. See Certificate of Analysis for expiration.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
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Inorganic Ventures 1000 g mL GLUTARATE 125mL
Inorganic Ventures' 1000 ppm (µg/mL) Glutarate for IC is a 125mL certified reference material set in a water matrix for stability. This glutarate standard is Traceable to NIST and manufactured in accordance with our stringent Quality Assurance guidelines. See Certificate of Analysis for expiration.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
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Sigma Aldrich Fine Chemicals Biosciences Sodium chlorite | 7758-19-2 | MFCD00003478 | 1kg
Sodium chlorite | Purity: 80% | MW:90.44 | 7758-19-2 | MFCD00003478 | 1kg
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Sigma Aldrich Fine Chemicals Biosciences Sodium chlorite technical grade, 80% | Purity: 80% | Mol Wt: 90.44 | 7758-19-2 | MFCD00003478 | 100G
Sodium chlorite technical grade, 80% | Purity: 80% | Mol Wt: 90.44 | 7758-19-2 | MFCD00003478 | 100G
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VEOLIA WTS IC STANDARD 25MG/L
NC1483126 IC STANDARD 25MG/L
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Inorganic Ventures 1000µg/mL PHOSPHATE 500mL
Inorganic Ventures' 1000 ppm (µg/mL) Phosphate for IC is a 500mL certified reference material set in a water matrix for stability. This phosphate standard is Traceable to NIST and manufactured in accordance with our stringent Quality Assurance guidelines. See Certificate of Analysis for expiration.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
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Inorganic Ventures 1 000µg/mL THIOSULFATE 500mL
Inorganic Ventures' 1000 ppm (µg/mL) Thiosulfate for IC is a 500mL certified reference material set in a water matrix for stability. This thiosulfate standard is Traceable to NIST and manufactured in accordance with our stringent Quality Assurance guidelines. See Certificate of Analysis for expiration.
ATTENTION: Inorganic Ventures is no longer supplying paper copies of Certificate of Analyses(CoA) and Safety Data Sheets (SDS). Please use this link to download your copies: https://www.inorganicventures.com/coa-sds-search
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Apexbio Technology LLC DTNB 69-78-3 1g
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DTNB (69-78-3) is a biochemical reagent that reacts specifically with free sulfhydryl (-SH) groups It is utilized to quantitatively detect thiol groups in biological samples DTNB exerts its activity by undergoing disulfide bond cleavage upon interaction with free thiols leading to the formation of a colored derivative 5-thio-2-nitrobenzoate (TNB) which is measurable by spectrophotometry at 412 nm Based on these properties DTNB is widely applied in the quantification of reduced glutathione (GSH) and assessment of thiol levels in tissues blood and cultured cells enabling studies of oxidative stress redox state and thiol-reactive drug screening
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Apexbio Technology LLC Adrenosterone 382-45-6 1g
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Adrenosterone (CAS 382-45-6) is a small-molecule inhibitor targeting 11- -hydroxysteroid dehydrogenase 1 It is designed to competitively inhibit this enzyme thereby modulating steroid metabolism pathways Adrenosterone exerts its biological activity primarily through enzymatic inhibition In human cancer cell studies Adrenosterone demonstrates inhibitory activity on metastatic progression Based on these pharmacological properties Adrenosterone holds research potential in studying steroid metabolism androgen receptor interactions endocrine regulation mechanisms and hormone-dependent diseases
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